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Cell Signaling Technology

From Alfawiki
Adapted from the English Wikipedia article Cell Signaling Technology, available under CC BY-SA 4.0Updated 28 November 2025
Cell Signaling Technology, Inc.
Company typePrivate
IndustryBiotechnology
Founded1999
Headquarters
Danvers, Massachusetts
,
United States
Area served
Worldwide
ProductsAntibodies, ELISA kits, ChIP kits, proteomic assay kits, reagents
Websitewww.cellsignal.com

Cell Signaling Technology, Inc. (CST) is a privately held company dedicated to creating and manufacturing antibodies, ELISA kits, ChIP kits, proteomic assay kits, and associated reagents that facilitate the investigation of cell signaling pathways vital to human health. The firm maintains an internal research division concentrating on cancer biology and has contributed extensively to peer-reviewed scientific literature.

History

Established in 1999 by researchers formerly affiliated with the Cell Signaling group at New England Biolabs (NEB), CST began its operations at the Cummings Center located in Beverly, Massachusetts. By late 2005, the company shifted its U.S. headquarters to the former King’s Grant Inn in Danvers, Massachusetts. Following substantial renovations, this site achieved LEED certification from the U.S. Green Building Council in 2007.

Between 2008 and 2009, CST broadened its global presence by founding subsidiaries in China, Japan, and the Netherlands. In 2013, production activities were transferred to an ISO9001 accredited facility situated in Beverly, Massachusetts.

From 2009 through 2013, CST was honored as one of the Boston Globe’s “Top 100 Places to Work.”

Research

In addition to product innovation and manufacturing, CST is engaged in advancing novel methodologies for signaling pathway analysis and mechanistic studies in cell biology, with a particular emphasis on oncology research.

CST also manages PhosphoSitePlus, a detailed online bioinformatics database that catalogs post-translational modifications (PTMs) such as phosphorylation, acetylation, methylation, ubiquitylation, and glycosylation across human, mouse, and rat proteins. This freely available resource aids scientific investigation and receives partial funding through NIH grants, including support from the NIH BD2K program.

Notable employees

External links