List of airlines of the United States

This compilation features airlines that hold an air operator's certificate issued by the Federal Aviation Administration in the United States.

Note: Destinations displayed in bold represent primary hubs, those in italics denote secondary hubs, and standard text indicates focus cities. For the legacy carriers American, Delta, and United, their most critical hubs are identified as primary hubs.

Mainline

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Regional

Airline	IATA	ICAO	Callsign	Primary hubs, secondary hubs	Founded	Notes
Alaska Airlines	AS	ASA	ALASKA	Seattle/Tacoma Anchorage Portland (OR) San Diego San Francisco Los Angeles	1932	Originally established as McGee Airways; operations commenced in 1944 under the Alaska Airlines name. In 2024, Hawaiian Airlines was integrated into the Alaska Air Group but continues to operate under its own brand.
Allegiant Air	G4	AAY	ALLEGIANT	Las Vegas Cincinnati Destin/Ft. Walton Beach Indianapolis Orlando/Sanford Pittsburgh Appleton Bellingham Des Moines Punta Gorda Grand Rapids St. Petersburg/Clearwater Phoenix/Mesa	1997	Launched as WestJet Express; began flight operations in 1998 under the Allegiant Air brand.
American Airlines	AA	AAL	AMERICAN	Dallas/Fort Worth Charlotte Miami Chicago–O'Hare Phoenix–Sky Harbor Philadelphia Washington–National New York–LaGuardia Los Angeles New York–JFK	1926	Started as American Airways; began service in 1936 as American Air Lines. Recognized as the largest airline worldwide by revenue and scheduled passenger miles flown in 2025.
Avelo Airlines	XP	VXP	AVELO	Burbank New Haven Hartford Lakeland Raleigh/Durham Santa Rosa Wilmington (DE) Wilmington (NC) Concord (NC)	1987	Initially known as Casino Express Airlines; commenced scheduled flights from Burbank, California, in April 2021.
Breeze Airways	MX	MXY	MOXY	'\'\'\'Charleston (SC) \'\'\' \'\' Hartford \'\' \'\' New Orleans \'\' \'\' Norfolk \'\' \'\' Providence \'\' \'\' Provo \'\' \'\' Tampa \'\'	2018	Founded originally as Moxy Airways; renamed due to trademark conflicts.
Delta Air Lines	DL	DAL	DELTA	Atlanta < br > Detroit < br > Minneapolis/St. Paul < br > New York–JFK < br > Salt Lake City < br > Boston < br > Los Angeles < br > New York–LaGuardia < br > Seattle/Tacoma	1924	Established as Huff Daland Dusters; began flight operations in 1929 under Delta Air Service.
Frontier Airlines	F9	FFT	FRONTIER FLIGHT	Denver < br > Atlanta < br > Chicago–O'Hare < br > Cincinnati < br > Cleveland < br > Las Vegas < br > Miami < br > Orlando < br > Philadelphia	1994
Hawaiian Airlines	HA	HAL	HAWAIIAN	Honolulu < br > Kahului	1929	Originally Inter-Island Airways, founded early in 1929; joined Alaska Air Group in 2024 while maintaining its own branding.
JetBlue	B6	JBU	JETBLUE	New York–JFK < br > Boston < br > Los Angeles < br > Fort Lauderdale < br > [[Orlando International Airport	Orlando ]] 1998 Founded as New Air; began flying in 2000 as JetBlue Airways.


Airline	Image	IATA	ICAO	Callsign	Main hubs, additional hubs	Established	Remarks
Air Wisconsin		ZW	AWI	WISCONSIN	Chicago–O'Hare Washington–Dulles	1965
Cape Air		9K	KAP	CAIR	Hyannis Billings Boston Nantucket St. Louis San Juan Albany Martha's Vineyard	1988
CommuteAir		C5	UCA	COMMUTAIR	Denver Newark Washington–Dulles	1989	Functions as United Express.
Contour Airlines		LF	VTE	VOLUNTEER	Smyrna (TN)	1982
Endeavor Air		9E	EDV	ENDEAVOR	Minneapolis/St. Paul Atlanta Cincinnati Detroit New York–JFK New York–LaGuardia Raleigh/Durham	1985	Originally Express Airlines I. Operates under Delta Connection.
Envoy Air		MQ	ENY	ENVOY	Dallas/Fort Worth Chicago–O'Hare Miami Phoenix–Sky Harbor	1984	Launched as American Eagle Airlines. Functions as American Eagle.
GoJet Airlines		G7	GJS	LINDBERGH	Chicago–O'Hare Denver	2004	Began service in 2005. Operates as United Express.
Horizon Air		QX	QXE	HORIZON	Seattle/Tacoma Portland (OR)	1981	Operates under Alaska Airlines.
Mesa Airlines		YV	ASH	AIR SHUTTLE	Houston-Intercontinental Washington–Dulles	1980	Founded as Mesa Air Shuttle. Majority of flights operate as United Express.
Piedmont Airlines		PT	PDT	PIEDMONT	Charlotte Philadelphia Washington–National	1961	Established as Henson Aviation in 1962. Functions as American Eagle.
PSA Airlines		OH	JIA	BLUE STREAK	Charlotte Philadelphia Washington–National	1979	Started as Vee Neal Airlines. Operates within the American Eagle network.
Ravn Alaska		7H	RVF	RAVN FLIGHT	Anchorage	1948	Originated as Economy Helicopters.
Republic Airways		YX	RPA	BRICKYARD	Indianapolis Columbus (OH) New York–LaGuardia As American Eagle: Kansas City Miami Philadelphia Pittsburgh Washington–National As United Express: Chicago–O'Hare Kansas City Newark Liberty International Airport, Pittsburgh, Washington-National As Delta Connection: 'O'Hare'	'1998'	'Commenced operations in 2005. Provides services for American Eagle, United Express, and Delta Connection.'
'SkyWest Airlines'	'Image'	'OO'	'SKW'	'SKYWEST'	'As Delta Connection: Atlanta Detroit Minneapolis/St. Paul Salt Lake City Boise Colorado Springs Los Angeles Seattle/Tacoma As United Express: Chicago-O’Hare Denver Houston-Intercontinental SFO Boise COS LAX As American Eagle: Dallas/Ft Worth Chicago-O’Hare LAX Phoenix-Sky Harbor As Alaska Airlines: Seattle/Tacoma Portland (OR)'	'1972'	'Provides operations for Delta Connection, United Express, American Eagle, and Alaska Airlines.'

Commuter

...

Airline	Image	IATA	ICAO	Callsign	Main hubs, secondary hubs	Established	Remarks
Advanced Air		AN	WSN	WINGSPAN	Hawthorne	2005	Operates EAS services at Silver City.
Bering Air		8E	BRG	BERING AIR	Nome Kotzebue Unalakleet	1979
Boutique Air		4B	BTQ	BOUTIQUE	Dallas/Ft. Worth Denver Phoenix–Sky Harbor	2007
Everts Air		5V	VTS	EVERTS	Fairbanks Anchorage	1978	Originally operated as Tatonduk Flying Service.
Gem Air		S6	MBI		Salmon	2014
Grand Canyon Airlines		YR	CVU	CANYON VIEW	Boulder City Grand Canyon Page	1927	Initially founded under the name Scenic Airways.
Grand Canyon Scenic Airlines		YR	SCE	SCENIC	Grand Canyon	1967
Grant Aviation		GV	GUN	HOOT	'Anchorage' (Ted Stevens Anchorage International Airport) Bethel Cold Bay Dillingham Emmonak Kenai King Salmon Unalaska/Dutch Harbor	1971	Originally known as Delta Air Services.
Griffing Flying Service					Port Clinton	1937
Island Airways					Charlevoix	1945	Started as McPhillips Flying Service.
JSX		XE	JSX	BIGSTRIPE		2016	Provides service for Taos Air since 2022.
Kenmore Air		M5	KEN	KENMORE	Kenmore Air Harbor Seattle–Lake Union Seaplane Base Seattle–Boeing Field	1946	Formerly known as Mines Collins Munro.
Key Lime Air		KG	LYM	KEY LIME	Centennial Airport Denver International Airport Rocky Mountain Metropolitan Airport Grand Junction Regional Airport	1997	Operates under Denver Air Connection branding.
Mokulele Airlines	[[File:Mokulele Express C208 N862MA OGG.jpg]\|100px]]	MW	MHO	MAHALO	Kailua–Kona (Kona International) Kahului	1994 Originally Mokulele Flight Service.
New England Airlines	[[File:New England Airlines Islander at Block Island State Airport 7-23-2015.jpg]\|100px]]	EJ	NEA	NEW ENGLAND	Westerly State Airport	1970
Penobscot Island Air					Knox County Regional Airport (Rockland)	2004
Reliant Air	[[File:Reliant Air Hangar Citation Danbury Municipal Airport KDXR (1).jpg]\|100px]]		RLI	RELIANT	Danbury Municipal Airport	1988

Charter

...' etc., continuing similarly with concise entries ...

Airline	IATA	ICAO	Callsign	Main hubs, secondary hubs	Established	Remarks
Air Charter Bahamas
Air Charter Express	FRG FREIGHT RUNNERS Milwaukee Mitchell International 1985
Air Flight Charters	FLL	Fort Lauderdale–Hollywood International 1987
Airshare	XSR AIRSHARE	2000 Founded as Executive Flight Services.
Berry Aviation	BYA BERRY San Marcos Regional 1983
Bighorn Airways	BHR BIGHORN AIR Sheridan County 1947
Choice Airways	CSX CHOICE AIR Fort Lauderdale Executive 2009
'''Eastern Air Express'''	'BBQ'	'EASTERN EXPRESS'	'Kansas City' 'Miami'	'2013'	'Started as ATX Air Services.'
'''Eastern Airlines, LLC'''	'2D'	'EAL'	'EASTERN'	'Kansas City'	'2010'	'Formerly Dynamic Airways.'
'''ExcelAire'''	'XLS'	'EXCELAIRE'	'Long Island/Islip'	'1993'
'''Global Crossing Airlines'''	'G6'	'GXA'	'GEMINI'	'Atlantic City Las Vegas Miami'	'2018'
'''Gryphon Airlines'''	'Y3'	'VOS'		'Kuwait International (Kuwait City)'
'''Havana Air'''			'Miami International'	'2007'	'Virtual airline.'
'''IBC Airways'''	'II'	'CSQ'	'CHASQUI'	'Ft. Lauderdale–Hollywood International'	'1991'
'Jet OUT'	'CRE'	'CREAM CITY'	'Upper Midwest, South Florida regions'	'2018'

Cargo airlines

..." and so forth continuing with similar concise entries ... %}

Air Ambulance Services

Airline	Image	IATA	ICAO	Callsign	Main hubs, secondary hubs	Founded	Remarks
7Air Cargo		TXG CARGO BOX Miami International 2020
21 Air	2I CSB CARGO SOUTH Piedmont Triad International (Greensboro) 2014
"ABX Air"	""	"GB"	"ABX"	"ABEX"	"Wilmington (OH)" (Wilmington Air Park) "Cincinnati" "Miami"	"1980"	"Originally Airborne Express. Operates some Amazon Air flights."
"Air Cargo Carriers"	""	"2Q"	"SNC"	"NIGHT CARGO"	"Milwaukee" "Cincinnati"	"1986"	""
"AirNet Express"	""	""	"USC"	"STAR CHECK"	"Columbus–Rickenbacker"	"1974"	"Started as Financial Air Express."
"Air Transport International"	""	"8C"	"ATN"	"AIR TRANSPORT"	"Wilmington (OH)" (Wilmington Air Park) "Cincinnati"	"1978"	"Founded as US Airways in 1980. Operates some Amazon Air flights."
"Alaska Central Express"	""	"KO"	"AER"	"ACE AIR"	"Anchorage"	"1996"	""
"Aloha Air Cargo"	""	"KH"	"AAH"	"ALOHA"	"Honolulu (Daniel K. Inouye International)"	"1946"	"Started as Trans-Pacific Airlines. Split from defunct Aloha Airlines in 2008."
"Alpine Air Express"	""	"5A"	"AIP"	"ALPINE AIR" "'Provo'" "Billings" "Sioux Falls" "1971" ""

Carrier	Main hubs, Additional hubs	Established	Remarks
AirMed International	Birmingham	1987	Initially launched under the name MEDjet International.
Air Methods	Denver–Centennial	1980
Critical Air Medicine		1984
Lifestar
Life Lion

Government-operated Airlines

Carrier	ICAO	Callsign	Main hubs, Additional hubs	Established	Remarks
Comco				2002
Janet	WWW	JANET	Las Vegas	1972
Justice Prisoner and Alien Transportation System	JUD	JUSTICE	Oklahoma City	1980	Service operations commenced in 1995.

References